Zhelong Xu Selected Research

Adenosine-5'-(N-ethylcarboxamide) (NECA)

1/2017	Roles of Endoplasmic Reticulum Stress in NECA-Induced Cardioprotection against Ischemia/Reperfusion Injury.
7/2010	The critical role of intracellular zinc in adenosine A(2) receptor activation induced cardioprotection against reperfusion injury.
1/2010	Role of autophagy in myocardial reperfusion injury.
11/2009	Adenosine A2A and A2B receptors work in concert to induce a strong protection against reperfusion injury in rat hearts.

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Zhelong Xu Research Topics

Disease

34	Reperfusion Injury 01/2022 - 11/2003
22	Ischemia 01/2022 - 10/2002
18	Infarction (Infarctions) 03/2021 - 10/2002
10	Myocardial Ischemia (Ischemic Heart Diseases) 01/2021 - 04/2004
7	Myocardial Infarction 01/2022 - 06/2005
4	Hypoxia (Hypoxemia) 01/2018 - 01/2014
3	Infections 01/2022 - 12/2013
3	Myocardial Reperfusion Injury 01/2021 - 07/2006
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2018 - 12/2013
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2017 - 03/2005
2	Chlamydophila Infections 01/2022 - 12/2013
2	Atherosclerosis 01/2022 - 01/2020
2	Neoplasms (Cancer) 06/2021 - 01/2020
2	Cardiotoxicity 06/2014 - 01/2014
2	Hypertension (High Blood Pressure) 01/2014 - 11/2006
1	Neoplasm Metastasis (Metastasis) 06/2021
1	Ovarian Neoplasms (Ovarian Cancer) 06/2021
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2020
1	Breast Neoplasms (Breast Cancer) 01/2020
1	Prostatic Neoplasms (Prostate Cancer) 01/2020
1	Inflammation (Inflammations) 09/2018
1	Starvation 01/2018
1	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 03/2017
1	Silicosis 01/2015
1	Heart Failure 06/2014

Drug/Important Bio-Agent (IBA)

15	ZincIBA 06/2021 - 09/2008
8	Mitochondrial Permeability Transition PoreIBA 01/2017 - 05/2006
8	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 11/2016 - 05/2006
6	zinc-binding protein (zinc binding protein)IBA 01/2022 - 01/2014
6	Adenosine (Adenocard)FDA LinkGeneric 07/2010 - 11/2003
4	Adenosine-5'-(N-ethylcarboxamide) (NECA)IBA 01/2017 - 11/2009
4	Glycogen Synthase KinasesIBA 01/2017 - 05/2006
4	Morphine (MS Contin)FDA LinkGeneric 01/2016 - 02/2008
4	Glycogen Synthase Kinase 3 betaIBA 02/2009 - 05/2006
3	Pharmaceutical PreparationsIBA 01/2018 - 11/2006
3	Purinergic P1 Receptors (Adenosine Receptor)IBA 01/2017 - 01/2010
3	AtractylosideIBA 11/2016 - 05/2006
3	Proteins (Proteins, Gene)FDA Link 11/2016 - 06/2005
3	Phosphotransferases (Kinase)IBA 01/2014 - 10/2007
3	Glycogen Synthase (Synthase I)IBA 01/2014 - 09/2008
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 01/2022
2	EstersIBA 01/2022 - 07/2006
2	Superoxides (Superoxide)IBA 01/2019 - 01/2018
2	Troponin IIBA 01/2019 - 01/2016
2	LipopolysaccharidesIBA 09/2018 - 01/2015
2	Mitochondrial DNA (mtDNA)IBA 01/2017 - 01/2016
2	ursodoxicoltaurineIBA 01/2017 - 11/2016
2	3-methyladenineIBA 01/2015 - 01/2010
2	Nitroprusside (Sodium Nitroprusside)FDA LinkGeneric 06/2014 - 01/2014
2	N,N,N',N'- tetrakis(2- pyridylmethyl)ethylenediamineIBA 01/2014 - 07/2010
2	ethylenediamine (ethylenediamine dihydroiodide)FDA Link 01/2014 - 07/2010
2	Chelating AgentsIBA 01/2014 - 07/2010
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2014 - 03/2005
2	BAY 60-6583IBA 05/2011 - 11/2009
2	N(6)- (3- iodobenzyl)- 5'- N- methylcarboxamidoadenosineIBA 11/2006 - 07/2006
2	SB 216763IBA 07/2006 - 05/2006
2	4- (7- ((2- 3- chloro- 2- thienyl)- 1- methyl- propylamino)- 3H- imidazo(4,5- b)pyridyl- 3- yl)cyclopentane carboxamideIBA 11/2003 - 10/2002
1	ProdrugsIBA 01/2022
1	Succinic Acid (Succinate)IBA 01/2022
1	Succinate Dehydrogenase (Fumarate Reductase)IBA 01/2022
1	neutrophil cytosol factor 67KIBA 01/2022
1	malonic acid (malonate)IBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 06/2021
1	HydrogelsIBA 03/2021
1	Matrix Metalloproteinases (MMPs)IBA 01/2021
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2021
1	Calcium-Calmodulin-Dependent Protein KinasesIBA 01/2021
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2021
1	CalciumIBA 01/2021
1	ApolipoproteinsIBA 01/2020
1	Toll-Like Receptor 2IBA 01/2020
1	LipidsIBA 01/2020
1	Chemokine ReceptorsIBA 01/2020
1	Focal Adhesion Protein-Tyrosine KinasesIBA 01/2020
1	Apolipoproteins E (ApoE)IBA 01/2020
1	Actins (F Actin)IBA 01/2020
1	triphenylphosphoniumIBA 01/2019
1	diazeniumdiolateIBA 01/2019
1	Nitric Oxide DonorsIBA 01/2019
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 09/2018
1	dodecyldimethylamine oxideIBA 09/2018
1	Fluorescent Dyes (Fluorescent Probes)IBA 09/2018
1	Sirolimus (Rapamycin)FDA Link 01/2018
1	Remifentanil (Ultiva)FDA Link 01/2018
1	MetalsIBA 01/2018
1	Alanine (L-Alanine)FDA Link 01/2018
1	Transcription Factors (Transcription Factor)IBA 01/2018
1	plerixafor FDA Link 11/2017
1	glucose-regulated proteinsIBA 01/2017
1	Glucose (Dextrose)FDA LinkGeneric 11/2016
1	src-Family KinasesIBA 01/2016
1	Silicon Dioxide (Silica)FDA LinkGeneric 01/2015
1	Proteasome Endopeptidase Complex (Proteasome)IBA 06/2014
1	triphenyltetrazoliumIBA 01/2014
1	Vasodilator Agents (Vasodilators)IBA 01/2014
1	kobophenol AIBA 01/2014
1	Toll-Like Receptors (Toll-Like Receptor)IBA 12/2013
1	Trace Elements (Biometals)IBA 12/2013
1	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 12/2013

Therapy/Procedure

3	Therapeutics 06/2021 - 10/2007